A Library of Clinical Studies and Research Papers

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  • Acute effects of a dietary non-starch polysaccharide supplement on cognitive performance in healthy middle-aged adults

    • Talitha Best

    Certain plant polysaccharides may provide psychological health benefits. The aim of this study was to evaluate whether they can acutely improve mood and cognitive function.

  • Polymannose Cognitive Immune Functioning Alzheimer's Disease 2013 Study

    • John E. Lewis

    Alzheimer’s disease (AD) is a leading killer of Americans, imparts a significant toll on the quality of life of the patient and primary caregiver, and results in inordinate costs in an already overburdened medical system. Prior studies on cholinesterase inhibitors among AD patients have shown minimal amelioration of disease symptoms and/or restoration of lost cognitive functioning. The effect of improved nutrition, particularly with dietary supplements, on cognitive functioning may offer an alternative strategy compared to standard treatment.

  • The Effect of Broad-Spectrum Dietary Supplementation on Quality of Life, Symptom Severity, and Functioning in Multiple Sclerosis

    • H. Reginald McDaniel

    Multiple sclerosis (MS) is a progressive neurodegenerative disease that exerts a significant quality-of-life toll on patients. According to the literature, broad-spectrum dietary supplementation including a variety of nutrients, polysaccharides, and compounds may improve the quality of life, functionality, and symptom severity in people with MS

  • The Effect of a Polysaccharide-Based Multi-nutrient Dietary Supplementation Regimen on Infections and Immune Functioning in Multiple Sclerosis

    • H. Reginald McDaniel

    Multiple sclerosis (MS) is a progressive neurodegenerative disease associated with increased infection rates, chronic inflammation, and premature death. Optimization of nutritional status via dietary supplementation may improve immune function in people suffering from MS and lead to decreased rates of infection.

  • Rice Bran Metabolome contains Amino Acids, Vitamins & Cofactors and Phytochemicals with Medicinal and nutritional properties

    • Iman Zarei

    Rice bran is a functional food that has shown protection against major chronic diseases (e.g. obesity, diabetes, cardiovascular disease and cancer) in animals and humans, and these health effects have been associated with the presence of bioactive phytochemicals.

  • Enhancement of Natural Killer Cell Activity in Healthy Adults by a Novel Oligo

    • Karriem H. Ali

    Rice Bran Arabinoxylan Compound (RBAC) is a nutritional supplement produced by enzymatic hydrolysis of hemicellulose B derived from rice bran. Several in vitro studies and clinical reports have shown RBAC to possess promising immunomodulating effects, specifically with respect to natural killer cell and cytokine activity.

  • Arabinoxylan Rice Bran (MGN-3) Enhances the Effects of Interventional Therapies for the Treatment of Hepatocellular Carcinoma: A Three-year Randomized Clinical Trial

    • Mai Hong Bang

    Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide with an estimated 626,000 new cases per year (1, 2). The prognosis for this cancer is poor, with a median survival time of less than six months. The etiology of HCC may be related to three major epidemiological factors, namely hepatitis B and C infection, aflatoxin exposure and cirrhosis (1, 3).

  • A review on the relation between Aloe Vera components and their Biologic effects

    • Seongwon Choi

    Aloe vera (Aloe barbadensis Miller) is a perennial succulent belonging to the Liliaceal family, and is called the healing plant or the silent healer. As a result of its use as folk medicine, it is claimed that aloe vera has wound and burn healing properties, and antiinflammatory, and immunomodulatory effects.

  • MGN-3 arabinoxylan rice bran modulates innate immunity in multiple myeloma patients

    • Dana Cholujova

    Dendritic cells (DCs) and natural killer (NK) cells are central components of innate immunity for controlling tumor growth. The therapeutic effects of certain anti-myeloma drugs are partially mediated by targeting the innate immune response.

  • The effect of dietary supplementation on brain-derived neurotrophic factor and cognitive functioning in Alzheimer’s dementia

    • Alicia Martin

    The objective of the present study was to investigate the effect of an aloe polymannose multinutrient complex (APMC) on pro brain-derived neurotrophic factor (BDNF) and mature BDNF in persons with moderate to severe Alzheimer’s dementia

  • Evidence-Based Review of BioBran/ MGN-3 Arabinoxylan Compound as a Complementary Therapy for Conventional Cancer Treatment

    • Soo Liang Ooi

    Conventional cancer treatment, including surgery, chemotherapy, and radiotherapy, may not be sufficient to eradicate all malignant cells and prevent recurrence. Intensive treatment often leads to a depressed immune system, drug resistance, and toxicity, hampering the treatment outcomes

  • Immunomodulatory dietary polysaccharides: a systematic review of the literature

    • Jane E Ramberg

    A large body of literature suggests that certain polysaccharides affect immune system function. Much of this literature, however, consists of in vitro studies or studies in which polysaccharides were injected. Their immunologic effects following oral administration is less clear. The purpose of this systematic review was to consolidate and evaluate the available data regarding the specific immunologic effects of dietary polysaccharides.

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